The 10th Shanghai International Conference on Radiation Oncology (SICRO) was held during August 10–11, 2018 in Shanghai, China. During the meeting, the Editorial Office of Precision Cancer Medicine is honored to conduct an interview with Prof. Philippe Lambin, Professor of Radiation Oncology at Maastricht University, The Netherlands. His main areas of interest are directed towards translational research in Radiation Biology with a specific focus on tumour hypoxia, functional imaging (CT-PET), lung and head and neck cancer.