Dr. Michael Milano is an associate professor of radiation oncology at the University of Rochester School of Medicine and Dentistry. He has just joined the Editorial Board of Precision Cancer Medicine since August 2018. He has been devoted to pursuing radiation oncology all through his career and treating and caring patients with cancer or benign brain tumors. This time, we are honored to interview Dr. Michael Milano to share with our readers his expertise in radiation oncology, his insights of cancer treatments in the perspective of precision medicine, and his valuable experience during his clinic and research practice.