@article{PCM5206,
author = {Elizabeth Colwell and Jalen Benson and Prasha Bhandari and Hao He and Joseph Shrager and Natalie Lui and Mark Berry and Leah Backhus},
title = {Differences in optimal timing of post-surgical surveillance for limited stage lung cancer patients and associations with outcomes},
journal = {Precision Cancer Medicine},
volume = {2},
number = {0},
year = {2019},
keywords = {},
abstract = {Background: Guidelines for post-operative surveillance for non-small cell lung cancer (NSCLC) are variable. Historically, providers have used a one-size fits all approach, such that surveillance guidelines incorporated few important prognostic indicators for recurrence and survival. The goal of this study was to determine optimal timing for detection of recurrence by CT scan and the association between surveillance CT and overall survival.
Methods: This was a retrospective, single institution series of patients undergoing surgical resection [2008– 2012] with stage I or II disease (AJCC 7th edition) with at least 6 months of follow-up.
Results: Recurrence occurred in 27.2% of patients at a median of 29.5 months following surgery. Recurrences peaked at 2–3 years following surgery for the entire cohort. For those detected on CT scan surveillance, stage I the peak timing for recurrence was at 25–36 months (year 3) whereas stage II peak timing was at 19–24 months (year 2) following resection. Timing of recurrences detected by any means differed significantly based on cancer stage with 81% (n=27) of recurrences occurring more than 24 months following surgery for stage I patients compared to 41% (n=17) of stage II patients (P},
issn = {2617-2216}, url = {https://pcm.amegroups.org/article/view/5206}
}